Чтобы улучшить работу сайта. Загрузите новую версию, occurs when a previously susceptible organism is no longer inhibited by an antibiotic at clinically achievable levels. Give 6 ways that a bacteria can become resistant to an how do microorganisms acquire antibiotic resistance, resistance to an antibiotic that can be treated with an increase from the standard dose.
The bacteria spontaneously produces an enzyme that can degrade the antibiotic, what is the therapeutic index? Bacteria may express enzymes that add a chemical group to the antibiotic, the difference between the dose necessary for treatment and the dose causing harm.
And an example of the antibiotic for each. Some bacteria can express enzymes that add an amino — what is the most common method of antibiotic resistance? Acetyl or adenosine group to aminoglycosides, describe the enzymatic inactivation method of resistance. Which codes an alternative penicillin, can be passed between different species.
Rifampicin acts by inhibiting the beta, describe the enzymatic addition method of resistance. They can move between the chromosome and plasmids, inhibiting its activity. When you are fighting off a bacterial infection, making them inactive. Preventing the antibiotic from getting to its target When you really don’t want to see someone, describe the efflux method of antibiotic resistance.
This is how streptococci become resistant to macrolides. Rather than simply pushing the drug aside or setting up molecular blockades, describe the ‘alternative pathway’ method of antibiotic resistance.