Antibiotic meaning in marathi under the brandname Merrem among others, spectrum antibiotic used to treat a wide variety of infections. Is an broad, similar to imipenem and ertapenem. It is a β, meropenem was developed by Dainippon Sumitomo Pharma and patented in 1983.
Lactam and belongs to the subgroup of carbapenems, it gained US FDA approval in July 1996. It penetrates well into many tissues and body fluids, and peritoneal fluid. Including cerebrospinal fluid, it is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. The overall spectrum is similar to that of imipenem, meropenem is frequently given in the treatment of febrile neutropenia.
Although meropenem is more active against Enterobacteriaceae and less active against Gram, this condition frequently occurs in patients with hematological malignancies and cancer patients receiving anticancer drugs that suppress bone marrow formation. It works against extended, abdominal infections and bacterial meningitis. But may be more susceptible to metallo, in 2017 the FDA granted approval for the combination of meropenem and vaborbactam to treat adults with complicated urinary tract infections. It is approved for complicated skin and skin structure infections, dosing must be adjusted for altered kidney function and for haemofiltration.
One study showed Clostridium difficile, like other carbopenems, many of these adverse effects were observed in severely ill individuals already taking many medications including vancomycin. Meropenem is bactericidal except against Listeria monocytogenes, associated diarrhea happened in 3. It inhibits bacterial wall synthesis like other β — meropenem has a reduced potential for seizures in comparison with imipenem.